| RK | PLAYER | FRANCHISE | OPP | IP | W | SV | ER | HW | K | ERA | WHIP |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | GERMÁN MÁRQUEZ (COL) ^ | Cambridge Crunch | MIA | 5.0 | 1 | 0 | 2 | 6 | 8 | 3.60 | 1.20 |
| 2. | JACOB DEGROM (NYM) ^ | Washington Beltways | @KC | 7.0 | 1 | 0 | 1 | 5 | 5 | 1.29 | 0.71 |
| 3. | DINELSON LAMET (SD) ^ | Las Vegas Aces | @PHI | 6.0 | 1 | 0 | 3 | 7 | 6 | 4.50 | 1.17 |
| 4. | ANTHONY DESCLAFANI (CIN) ^ | Reading Railroaders | STL | 5.0 | 1 | 0 | 1 | 8 | 4 | 1.80 | 1.60 |
| 5. | JON LESTER (CHC) ^ | Colorado Wookiees | @PIT | 6.0 | 1 | 0 | 0 | 9 | 3 | 0.00 | 1.50 |
| 6. | SEAN NEWCOMB (ATL) | Pasadena Marauding Gods | LAD | 1.1 | 1 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
| 7. | KIRBY YATES (SD) | Pasadena Marauding Gods | @PHI | 1.0 | 0 | 1 | 0 | 0 | 1 | 0.00 | 0.00 |
| 8. | SETH LUGO (NYM) | Pasadena Marauding Gods | @KC | 1.0 | 0 | 1 | 0 | 0 | 1 | 0.00 | 0.00 |
| 9. | MARK MELANCON (ATL) | Pasadena Marauding Gods | LAD | 1.0 | 0 | 1 | 0 | 1 | 1 | 0.00 | 1.00 |
| 10. | SHANE GREENE (ATL) | Cambridge Crunch | LAD | 1.0 | 0 | 0 | 0 | 0 | 3 | 0.00 | 0.00 |
| 11. | MICHAEL LORENZEN (CIN) | Colorado Wookiees | STL | 2.0 | 0 | 0 | 0 | 1 | 3 | 0.00 | 0.50 |
| 12. | ANDRES MUÑOZ (SD) | Carolina Thunderdogs | @PHI | 1.0 | 0 | 0 | 0 | 0 | 2 | 0.00 | 0.00 |
| 13. | TYLER CHATWOOD (CHC) | Virginia Hat Lineup | @PIT | 2.0 | 0 | 0 | 0 | 1 | 2 | 0.00 | 0.50 |
| 14. | MIKE FOLTYNEWICZ (ATL) ^ | Crowleys Ridge Roosters | LAD | 4.2 | 0 | 0 | 2 | 10 | 5 | 3.86 | 2.14 |
| 15. | JUNIOR FERNÁNDEZ (STL) | Las Vegas Aces | @CIN | 1.0 | 0 | 0 | 0 | 3 | 2 | 0.00 | 3.00 |
| 16. | HYUN-JIN RYU (LAD) ^ | Colorado Wookiees | @ATL | 5.2 | 0 | 0 | 4 | 7 | 5 | 6.35 | 1.24 |
| 17. | JOSH HADER (MIL) | Reading Railroaders | @WAS | 1.0 | 0 | 0 | 1 | 4 | 3 | 9.00 | 4.00 |
| 18. | LUKE JACKSON (ATL) | Virginia Hat Lineup | LAD | 1.0 | 0 | 0 | 1 | 2 | 2 | 9.00 | 2.00 |
| 19. | MILES MIKOLAS (STL) ^ | Las Vegas Aces | @CIN | 5.0 | 0 | 0 | 5 | 9 | 5 | 9.00 | 1.80 |
| 20. | ANÍBAL SÁNCHEZ (WSH) ^ | Pasadena Marauding Gods | MIL | 4.0 | 0 | 0 | 5 | 12 | 5 | 11.25 | 3.00 |
| 21. | NICK PIVETTA (PHI) | Las Vegas Aces | SD | 1.1 | 0 | 0 | 2 | 4 | 1 | 13.50 | 3.00 |
| 22. | ADAM CONLEY (MIA) | Crowleys Ridge Roosters | @COL | 0.2 | 0 | 0 | 3 | 4 | 0 | 40.50 | 6.00 |
| 23. | SEAN DOOLITTLE (WSH) | Cambridge Crunch | MIL | 0.1 | 0 | 0 | 4 | 4 | 0 | 108.00 | 12.00 |