| RK | PLAYER | FRANCHISE | OPP | IP | W | SV | ER | HW | K | ERA | WHIP |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | MILES MIKOLAS (STL) ^ | Colorado Wookiees | @CWS | 6.0 | 1 | 0 | 2 | 4 | 6 | 3.00 | 0.67 |
| 2. | DEREK HOLLAND (SF) ^ | A Team Has No Name | CHC | 6.1 | 0 | 0 | 1 | 5 | 8 | 1.42 | 0.79 |
| 3. | JOSE QUINTANA (CHC) ^ | Crowleys Ridge Roosters | @SF | 6.0 | 1 | 0 | 0 | 5 | 3 | 0.00 | 0.83 |
| 4. | TYLER ANDERSON (COL) ^ | Carolina Thunderdogs | ARI | 6.0 | 0 | 0 | 1 | 7 | 8 | 1.50 | 1.17 |
| 5. | RAISEL IGLESIAS (CIN) | Greendale Broken Arrows | @CLE | 1.0 | 0 | 1 | 0 | 1 | 2 | 0.00 | 1.00 |
| 6. | JULIO TEHERAN (ATL) ^ | Washington Beltways | TOR | 6.2 | 0 | 0 | 1 | 6 | 5 | 1.35 | 0.90 |
| 7. | CORBIN BURNES (MIL) | Canandaigua Aces | @MIA | 2.0 | 0 | 1 | 0 | 0 | 1 | 0.00 | 0.00 |
| 8. | RICH HILL (LAD) ^ | Virginia Hat Lineup | @SD | 7.0 | 0 | 0 | 4 | 9 | 7 | 5.14 | 1.29 |
| 9. | PATRICK CORBIN (ARI) ^ | A Team Has No Name | @COL | 4.1 | 0 | 0 | 2 | 9 | 6 | 4.15 | 2.08 |
| 10. | STEVE CISHEK (CHC) | Virginia Hat Lineup | @SF | 1.0 | 0 | 1 | 0 | 0 | 0 | 0.00 | 0.00 |
| 11. | JHOULYS CHACÍN (MIL) ^ | Virginia Hat Lineup | @MIA | 5.2 | 1 | 0 | 4 | 10 | 3 | 6.35 | 1.76 |
| 12. | BRAD BOXBERGER (ARI) | Dabigu | @COL | 1.0 | 0 | 1 | 0 | 1 | 0 | 0.00 | 1.00 |
| 13. | KELVIN HERRERA (WSH) | A Team Has No Name | @PIT | 1.0 | 0 | 0 | 0 | 3 | 2 | 0.00 | 3.00 |
| 14. | JUSTIN WILSON (CHC) | Cambridge Crunch | @SF | 1.0 | 0 | 0 | 0 | 0 | 1 | 0.00 | 0.00 |
| 15. | KIRBY YATES (SD) | Pasadena Marauding Gods | LAD | 0.1 | 0 | 0 | 0 | 0 | 1 | 0.00 | 0.00 |
| 16. | SAM DYSON (SF) | Pasadena Marauding Gods | CHC | 1.2 | 0 | 0 | 1 | 3 | 2 | 5.40 | 1.80 |
| 17. | JEREMY JEFFRESS (MIL) | A Team Has No Name | @MIA | 1.0 | 0 | 0 | 0 | 2 | 1 | 0.00 | 2.00 |
| 18. | JOHNNY CUETO (SF) ^ | Pasadena Marauding Gods | CHC | 0.0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
| 19. | ADAM OTTAVINO (COL) | Dabigu | ARI | 1.0 | 0 | 0 | 0 | 2 | 0 | 0.00 | 2.00 |
| 20. | ARCHIE BRADLEY (ARI) | Canandaigua Aces | @COL | 0.2 | 0 | 0 | 1 | 3 | 0 | 13.50 | 4.50 |
| 21. | A.J. MINTER (ATL) | Pasadena Marauding Gods | TOR | 0.1 | 0 | 0 | 3 | 3 | 0 | 81.00 | 9.00 |