| RK | PLAYER | FRANCHISE | OPP | IP | W | SV | ER | HW | K | ERA | WHIP |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | JACOB DEGROM (NYM) ^ | Virginia Hat Lineup | @ATL | 8.1 | 1 | 0 | 2 | 5 | 10 | 2.16 | 0.60 |
| 2. | JORDAN YAMAMOTO (MIA) ^ | Las Vegas Aces | @STL | 7.0 | 1 | 0 | 0 | 4 | 7 | 0.00 | 0.57 |
| 3. | CLAYTON KERSHAW (LAD) ^ | Cambridge Crunch | SF | 7.0 | 1 | 0 | 0 | 5 | 6 | 0.00 | 0.71 |
| 4. | COLE HAMELS (CHC) ^ | Pasadena Marauding Gods | CWS | 7.0 | 0 | 0 | 1 | 8 | 8 | 1.29 | 1.14 |
| 5. | ANTHONY DESCLAFANI (CIN) ^ | Reading Railroaders | HOU | 5.1 | 1 | 0 | 1 | 7 | 4 | 1.69 | 1.31 |
| 6. | JACK FLAHERTY (STL) ^ | Washington Beltways | MIA | 7.0 | 0 | 0 | 3 | 5 | 8 | 3.86 | 0.71 |
| 7. | KIRBY YATES (SD) | Pasadena Marauding Gods | MIL | 1.0 | 0 | 1 | 0 | 1 | 2 | 0.00 | 1.00 |
| 8. | CORBIN BURNES (MIL) | Carolina Thunderdogs | @SD | 1.0 | 0 | 0 | 0 | 0 | 3 | 0.00 | 0.00 |
| 9. | BRANDON WOODRUFF (MIL) ^ | Carolina Thunderdogs | @SD | 6.0 | 0 | 0 | 4 | 8 | 6 | 6.00 | 1.33 |
| 10. | RAISEL IGLESIAS (CIN) | Greendale Broken Arrows | HOU | 0.2 | 0 | 0 | 0 | 0 | 2 | 0.00 | 0.00 |
| 11. | MERRILL KELLY (ARI) ^ | Greendale Broken Arrows | COL | 6.0 | 0 | 0 | 5 | 8 | 5 | 7.50 | 1.33 |
| 12. | SERGIO ROMO (MIA) | Dabigu | @STL | 1.1 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
| 13. | JAKE ARRIETA (PHI) ^ | Washington Beltways | @WAS | 0.0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
| 14. | PATRICK CORBIN (WSH) ^ | Las Vegas Aces | PHI | 0.0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
| 15. | ZACH EFLIN (PHI) ^ | Las Vegas Aces | @WAS | 0.0 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0.00 |
| 16. | TOUKI TOUSSAINT (ATL) | Carolina Thunderdogs | NYM | 2.0 | 0 | 0 | 2 | 5 | 2 | 9.00 | 2.50 |
| 17. | JOHN BREBBIA (STL) | Dabigu | MIA | 0.2 | 0 | 0 | 1 | 3 | 1 | 13.50 | 4.50 |
| 18. | PEDRO STROP (CHC) | Greendale Broken Arrows | CWS | 0.1 | 0 | 0 | 2 | 2 | 0 | 54.00 | 6.00 |
| 19. | AMIR GARRETT (CIN) | Washington Beltways | HOU | 0.2 | 0 | 0 | 2 | 3 | 0 | 27.00 | 4.50 |
| 20. | JULIO TEHERAN (ATL) ^ | Dabigu | NYM | 4.0 | 0 | 0 | 6 | 11 | 3 | 13.50 | 2.75 |